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What are moles?
Moles are common,
usually harmless, skin lesions. They are correctly called
melanocytic naevi as they are due to a proliferation of the pigment
cells, melanocytes. Moles can be flat or protruding. They
vary in colour from pink flesh tones to dark brown or black. The
number of moles a person has depends on genetic factors and on sun
exposure; most New Zealanders have 20 - 50 of them.
Melanocytic Naevi may
be present at birth (congenital) but more usually begin to grow
during childhood. New moles can appear at any age though incidence
does decrease with age. Early naevus cells form nests on the
junction between the epidermis (outer layer of the skin) and the
dermis (inner layer) so are known as junctional naevi. These are
flat moles.
Naevus cells can also
form in the epidermis and the dermis (compound naevi) or may be
found in the dermis (intradermal naevi). These moles are thickened
and often protrude from the skin surface. Heavily pigmented dermal
naevi often appear blue (blue naevi).
Moles may darken
following sun exposure or during pregnancy. During adulthood they
may lose their pigmentation, and they may even disappear in old age.
ATYPICAL MOLES (Dysplastic
Naevi)
Atypical Naevi, also
called Clarks Naevi or Dysplastic Naevi, are moles that have unusual
features such as an indistinct edge and/or larger size. They often
resemble a cancerous mole (melanoma), but are actually benign.
Because of their worrying appearance, they are often removed.
Dermoscopic examination can be very helpful in distinguishing these
from melanomas. People with atypical naevi have an increased risk of
developing melanoma.
CONGENITAL
PIGMENTED NAEVUS (CPN)
This is the name for a
mole present at birth. One in a hundred babies has a congenital
naevus varying in size from a few millimetres in diameter to
covering half the baby's skin. There may be an increased risk of
melanoma developing within congenital naevi, especially very large
ones, so if any change has been noted it should be checked.
HALO NAEVUS
Sometimes the skin
around a mole losses its colour so the mole appears to be surrounded
by a white ring. This 'halo' naevus occurs most often in children
and teenagers. It is harmless, and with time the central mole and
white ring disappear. It is caused by the body’s immune system
attacking the melanocytes.
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